Major Science FS-50L SIP Fermentation System (50L, 130 x 95 x 295 cm)

Capacity:   50 L

Total volume:   67 L

Working volume:   50 L

Dimension:   130 x 95 x 295 cm

Vessel and jacket maximum working pressure: 3 bar (43.5 psig) / 4 bar (58 psig)

Type: Double layered fully enclosed capsule-type tank

Material: Direct contact to medium - 316L stainless steel; all others - 304 stainless steel

Surface finish: Interior polish ≦ 25 Ra/in (0.6 μm) Mechanical polishing; Electropolish optional

Exterior polish ≦ 32 Ra/in (0.8 μm) Mechanical polishing; Electropolish optional

Ports:
Ports designed according to user requirements

Piping and valve materials:
Parts that directly contact with the product/medium uses 316L stainless steel (≤25 Ra/in) internal polished tubing (BPE standard) :

A. Internal EP polished diaphragm type pneumatic valve and manual valve (BPE standard)

B. Tubing all welded with orbital welding

C. Vessel bottom drain uses a diaphragm valve, to minimize dead volume

D. Piping designed for ease of transfer to scale up (can be used as a seed fermentation system) or downstream process

Parts that do not directly contact product/medium

A. Constructed with 304 stainless steel

Controller: 10.4” color industrial touch screen

Setting
* Automated sterilization process

* Automated fermentation program

DO

* 0-200%, Control range:0-100%, adjustable

* Software electrode calibration, with automatic temperature compensation function

* Includes one set of side-inserted stainless steel autoclavable DO electrode

* DO Stat features with intelligent feeding

pH

* PID control with adjustable deadband

* Control range0 to 14 (2-12 for maximum precision), resolution: 0.01 pH

* Calibration function with automatic temperature compensation function

* Includes one set of side-inserted, autoclavable pH probe with stainless steel housing

* pH Stat features with intelligent feeding

Pump

* Built-in peristaltic pumps

* Each feeding pump can run adjustable 15-step program

* Each pump can be adjusted for speed, forward and backward direction, and manual or automatic mode

* Each of the four peristaltic pumps can be designated for different functions: acid pump, base pump, antifoam pump, or substrate feeding pump

* Optional fifth and six peristaltic pump available

Temperature

* Vessel temperature is measured with a side-inserted PT-100 temperature probe and maintained using PID control.

* Control range: 0-130°C, ±0.1°C. Operational range up to 0-60°C

Agitation

* Manual or automatic control of agitation speed

* 15-step program to change speed, or use DO cascade control

Air supply and exhaust Gas supply and dehumidifer: uses in-house air compressor or air dehumidifier

* Includes re-useable, autoclavable 0.2μm air filter for gas inlet

* Gas Inlet (air)

Includes mass flow controller:

2 vvm maximum according to the vessel capacity

* Gas Inlet (oxygen)

Includes pure oxygen rotameter (manual flow control):

1 vvm maximum according to the vessel capacity

* Includes oxygen gas solenoid valve, with automatic pulsed time control

Air outlet / Exhaust

* Exhaust port with stainless steel condenser

* Includes re-useable, autoclavable 0.2μm air filter

* Includes automated adjustable gas outlet valve to adjust vessel back pressure

* Can control manually or automatically via software

Utility Requirement

Capacity:   50L

Power: Three phase 220V or 380V (note: can be customized to local standard)

Air:
At least 6 bar

100 L/min flow rate

Dehumidified

Oil-free

Peripheral factory water supply: Cooling water (tap water, at least 15 °C below working temperature, must be soft water) ;

Pressure at least 2 bar

Process water: RO Water

Plant steam: ≥ 2 bar; dry steam with no entrained condensate

Process steam: ≥ 2 bar; dry steam with no entrained condensate

Drain: In situ drain; ≥ 1"

*Customization on the SIP Fermentation system available upon request.